Guggul and oral contraceptives
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If used at the same time, there is a moderate risk that guggul will interfere with treatment levels of a significant number of certain prescription drugs e. Drugs that interact with this enzyme treat a wide range of conditions, including treatments for high blood pressure, cancer, high cholesterol, fungal infections, abnormal blood sugar levels, and pain. In two small clinical trials involving healthy human participants, gugulipid significantly reduced the bioavailability in the blood of two prescription drugs used for high blood pressure— propranolol and diltiazem. Since guggulsterones are phytoesterols they can behave like estrogen in the body and increase adverse reactions from drugs containing estrogen e. Although this interaction is labeled only theoretical based on chemical properties of guggulsterones, it is considered a probable reaction. Experts warn against taking guggul if you are on any type of estrogen since the interaction is considered high risk of adverse effects.
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Update on Oral Contraceptive Pills
Guggul: Benefits, Side Effects, Dosage, and Interactions
It is a small flowering plant from the Burseraceae family. It has a very dark softwood color, which produces a specific resin called oleoresin or guggulipid. Guggul has been a well-known herb used for treatment in the Ayurvedic medicine for at least three thousand years, and is considered to help the body feed itself using the accumulated fat. Its juice is extracted by making a small hole in the bark of the tree , from which its aromatic resin flows slowly. When the drop dries out, it is already ready to be collected.
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Guggul Side Effects
Drug information provided by: IBM Micromedex. This medicine usually contains two types of hormones, estrogens and progestins and, when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented. Although oral contraceptives have other effects that help prevent a pregnancy from occurring, this is the main action.
Extracts from the gum resin of the Commiphora mukul tree have been used by traditional Ayurveda medicine as a natural herbal remedy for thousands of years. Gugulipid is believed to be therapeutic for a variety of health conditions—including acne. Modern science has recently revealed that the active constituent of gugulipid is a plant sterol, guggulsterone.
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